Kuan-Teh Jeang Selected Research

T-Cell Leukemia (Leukemia, T Cell)

4/2012	Unstabilized DNA breaks in HTLV-1 Tax expressing cells correlate with functional targeting of Ku80, not PKcs, XRCC4, or H2AX.
11/2011	MicroRNAs and human retroviruses.
7/2011	Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling.
5/2010	Induction of reactive oxygen species by human T-cell leukemia virus type 1 tax correlates with DNA damage and expression of cellular senescence marker.
4/2009	Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB.
11/2008	Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human T-cell lymphotrophic virus 1.
2/2007	Human T-cell leukemia virus oncoprotein tax represses nuclear receptor-dependent transcription by targeting coactivator TAX1BP1.
7/2006	TORC1 and TORC2 coactivators are required for tax activation of the human T-cell leukemia virus type 1 long terminal repeats.
5/2006	An alternative splice product of IkappaB kinase (IKKgamma), IKKgamma-delta, differentially mediates cytokine and human T-cell leukemia virus type 1 tax-induced NF-kappaB activation.
3/2006	Role for Akt/protein kinase B and activator protein-1 in cellular proliferation induced by the human T-cell leukemia virus type 1 tax oncoprotein.

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Kuan-Teh Jeang Research Topics

Disease

21	T-Cell Leukemia (Leukemia, T Cell) 04/2012 - 05/2002
17	Neoplasms (Cancer) 12/2012 - 08/2002
9	Infections 11/2012 - 09/2002
6	Virus Diseases (Viral Diseases) 12/2012 - 01/2007
6	Carcinogenesis 08/2010 - 08/2005
4	Inflammation (Inflammations) 01/2013 - 01/2006
4	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 12/2012 - 05/2002
4	Aneuploidy (Aneuploid) 10/2009 - 04/2006
3	Acquired Immunodeficiency Syndrome (AIDS) 01/2006 - 12/2002
2	Fever (Fevers) 11/2013 - 01/2013
2	Leukemia 09/2012 - 05/2002
2	Laminopathies 09/2012 - 04/2012
2	Carcinoma (Carcinomatosis) 10/2007 - 08/2005
2	Genomic Instability 07/2006 - 07/2002
2	Chromosomal Instability (Chromosome Stability) 04/2006 - 07/2005
1	Aneurysm (Aneurysms) 11/2013
1	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 11/2013
1	High-Frequency Hearing Loss 02/2013
1	Hearing Loss (Hearing Impairment) 02/2013
1	MYD88 Deficiency 01/2013
1	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 09/2012
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 09/2012
1	Liver Neoplasms (Liver Cancer) 01/2011
1	Hepatocellular Carcinoma (Hepatoma) 01/2011
1	Disease Progression 10/2010
1	Protein Deficiency 12/2008
1	Pituitary Neoplasms (Pituitary Adenoma) 08/2007
1	HIV Infections (HIV Infection) 01/2007
1	Burkitt Lymphoma (Burkitt's Lymphoma) 02/2006
1	Necrosis 02/2006
1	Epstein-Barr Virus Infections 02/2006
1	Inborn Genetic Diseases (Disease, Hereditary) 10/2003
1	Simian Acquired Immunodeficiency Syndrome 12/2002

Drug/Important Bio-Agent (IBA)

15	Oncogene Proteins (Oncogene Protein)IBA 04/2012 - 05/2002
13	Proteins (Proteins, Gene)FDA Link 11/2013 - 08/2005
10	MicroRNAs (MicroRNA)IBA 12/2012 - 01/2006
7	NF-kappa B (NF-kB)IBA 07/2011 - 07/2005
4	Small Interfering RNA (siRNA)IBA 08/2011 - 05/2005
4	tax Gene Products (tax Gene Product)IBA 07/2006 - 09/2005
3	Messenger RNA (mRNA)IBA 07/2009 - 02/2006
2	Intravenous Immunoglobulins (IVIG)FDA Link 11/2013 - 01/2013
2	UbiquitinIBA 01/2013 - 04/2006
2	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)IBA 01/2011 - 11/2008
2	Nuclear Proteins (Protein, Nuclear)IBA 11/2008 - 10/2007
2	I-kappa B KinaseIBA 05/2006 - 02/2006
2	DNA (Deoxyribonucleic Acid)IBA 01/2004 - 07/2002
1	Sorting NexinsIBA 11/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2013
1	Phosphoprotein Phosphatases (Phosphatases, Protein)IBA 12/2012
1	Pharmaceutical PreparationsIBA 09/2012
1	BenzodiazepinesIBA 09/2012
1	Core Binding Factors (Core-Binding Factor)IBA 09/2012
1	Transcription Factors (Transcription Factor)IBA 09/2012
1	Ubiquitin-Specific ProteasesIBA 07/2011
1	TNF Receptor-Associated Factor 6 (TRAF6)IBA 07/2011
1	rho GTPase-activating proteinIBA 01/2011
1	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2010
1	Peptidylprolyl Isomerase (Prolyl Isomerase)IBA 04/2009
1	Polo-Like Kinase 1IBA 12/2008
1	Phosphotransferases (Kinase)IBA 12/2008
1	3' Untranslated Regions (3' UTR)IBA 11/2008
1	ProteomeIBA 10/2007
1	SecurinIBA 08/2007
1	Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA 02/2007
1	Vincristine (Oncovin)FDA LinkGeneric 01/2007
1	Mechanistic Target of Rapamycin Complex 2IBA 07/2006
1	Mechanistic Target of Rapamycin Complex 1IBA 07/2006
1	CytokinesIBA 05/2006
1	delta proteinIBA 05/2006
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 03/2006
1	Transcription Factor AP-1 (Transcription Factor AP 1)IBA 03/2006
1	NF-KappaB Inhibitor alphaIBA 02/2006
1	Membrane Proteins (Integral Membrane Proteins)IBA 02/2006
1	NF-kappaB-Inducing KinaseIBA 02/2006
1	VaccinesIBA 01/2006
1	Cyclin-Dependent Kinases (cdk Proteins)IBA 09/2005
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 08/2005
1	Ku AutoantigenIBA 07/2005
1	Tumor Suppressor Protein p53IBA 07/2005
1	Nucleic AcidsIBA 05/2005
1	polyarginineIBA 11/2004
1	FurinIBA 11/2004
1	PhosphoproteinsIBA 11/2004
1	Human T-lymphotrophic virus 1 tax proteinIBA 07/2004
1	IntegrasesIBA 01/2004
1	EnzymesIBA 10/2003
1	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2003
1	RNA (Ribonucleic Acid)IBA 10/2003
1	Peptide Hydrolases (Proteases)FDA Link 10/2003
1	Telomerase (Telomerase Reverse Transcriptase)IBA 06/2003
1	RibonucleoproteinsIBA 06/2003
1	SeleniumIBA 12/2002
1	NucleotidesIBA 08/2002
1	Codon (Codons)IBA 08/2002
1	Cyclin-Dependent Kinase 4IBA 05/2002
1	Retinoblastoma ProteinIBA 05/2002

Therapy/Procedure

2	Therapeutics 12/2011 - 10/2003
1	Drug Therapy (Chemotherapy) 12/2012
1	RNAi Therapeutics 01/2007
1	Aftercare (After-Treatment) 01/2007